Introduction. Low levels of nasal NO have been associated with increased propensity to rhinosinusitis and respiratory tract\ninfections. Our objective was to describe nasalNOlevels in HIV-infected individuals versus healthy controls and determine possible\nrisk factors for reduced nasal NO levels. Materials and Methods. HIV-infected individuals and healthy controls were recruited.\nParticipants underwent nasal NO testing by standardized methods using a CLD88 chemiluminescence analyzer and completed the\nSinonasal Outcome Test-20 (SNOT-20) on symptoms of rhinosinusitis. Results. Participants included 41 HIV-infected individuals\nwith suppressed VL on antiretroviral therapy (ART group), 5HIV-infected individuals with detectable VL off ART (viremic group),\nand 12 healthy controls (HC group).Mean nasal NO level was 253 (�±77) nL/min in the ART group, 213 (�±48) nL/min in the viremic\ngroup, and 289 (�±68) nL/min in the HC group (
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